Nichols Canyon is an area in the Hollywood Hills of Los Angeles.  It begins at Hollywood Boulevard on its south end and snakes its way north into the hills below Mulholland Drive. Nichols Canyon has two large year round water falls over 100' high, and several natural and man made small water falls. The two larger falls are the only natural water falls in the City of Los Angeles. The stream that flows through the bottom of Nichols Canyon attracts coyotes, frogs, deer, raccoons, skunks, rabbits and other wildlife. Hawks can often be seen circling the area as well. Home to many celebrities throughout the years, Nichols Canyon is a favorite jogging and cyclist road.

There are many stories to be told about the Canyon. For instance, on the evening of May 13, 1874 a sheriff's posse from Los Angeles camped near the mouth of Nichols Canyon a mile and a quarter northeast of Greek George's ranch house. The next morning, in a shoot out at Greek George's, they captured the Mexican bandit Tiburcio Vasquez. The present day Los Angeles County Park of Vasquez Rocks was one of his favorite hideouts.